Update: Two more users reported the same problem and it looks like it’s actually the Adobe PDF add-in causing the problem! I noticed that all 3 users have this add-in. I didn’t uninstall it because they’re using it, but what I did to fix this problem was I installed and enabled one of the add-ins that is part of Office 2007 and all their Excel files started loading fast again :).

Original Post:

You may also see the error message below:

Cannot find the file ‘PathToFile‘ (or one of its components). Make sure the path and filename are correct and that all required libraries are available.

One of our users who we just upgraded to Microsoft Office 2007 had this problem this morning. When she double-clicks on an Excel file, the Excel program opens but the file itself doesn’t open until she clicks the minimize or maximize buttons.

The problem seems to have something to do with DDE.

To fix this problem, do the following:

1. Open Windows Explorer.
2. Go to Tools -> Folder Options -> File Types tab. Select XLS then click the Advanced button.
3. Select Open, then click the Edit button.
4. Under Application used to perform function: make sure there’s a quotation mark before and after %1 just like the picture below:

5. Uncheck Use DDE.

Credit goes to the posts from this site.